Table 2.
Summary of clinical characteristics between patients with ALS and normal controls in subgroups.
| R_limb-onset (n = 20) |
R_NC (n = 20) |
P 1 | L_limb-onset (n = 16) |
L_NC (n = 16) |
P 2 | P 3 | |
|---|---|---|---|---|---|---|---|
| Age | 57.5 ± 8.1 (55.8 ± 8.0)a |
56.0 ± 6.4 | 0.520 | 48.4 + 9.7 (47.4 ± 9.9)a |
50.6 ± 9.0 | 0.515 | 0.005 0.008a |
| Male, n | 14 | 14 | 1 | 9 | 9 | 1 | 0.307 |
| MMSE | 27.5 ± 2.1 | 28.8 ± 1.2 | 0.051 | 28.9 ± 1.6 | 29.2 ± 1.0 | 0.508 | 0.055 |
| ALSFRS | 27.7 ± 6.6 | n/a | — | 32.3 ± 6.3 | n/a | — | 0.043 |
| Disease duration (months) | 20.9 ± 20.8 | n/a | — | 13.8 ± 6.9 | n/a | — | 0.239 |
| Disease progression rate | 1.12 ± 0.88 | n/a | — | 0.66 ± 0.62 | n/a | — | 0.088 |
R_NC: normal controls corresponding to patients with right limb-onset; L_NC: normal controls corresponding to patients with left limb-onset. aMean age of disease onset in patients with right and left limb-onset and corresponding P value.
P 1 represents the statistical differences in ALS patients with right limb-onset and corresponding normal controls. P 2 represents the statistical differences in ALS patients with left limb-onset and corresponding normal controls. P 3 represents the statistical differences in subgroups between ALS patients with right and left limb-onset.