Table 3.
Global-brain volumetric measurements in total group of patients with ALS and normal controls by SIENAX.
| NC | ALS | P 1 | P 2 | |
|---|---|---|---|---|
| BPF | 0.97 ± 0.01 | 0.96 ± 0.01 | 0.009 | 0.000 |
| NCV (mm3) | 584.0 ± 34.6 | 558.7 ± 30.2 | 0.001 | 0.000 |
| NGMV (mm3) | 737.7 ± 46.4 | 699.4 ± 105.9 | 0.016 | 0.004 |
| NWMV (mm3) | 697.0 ± 38.2 | 675.9 ± 30.1 | 0.006 | 0.004 |
BPF: brain parenchyma fraction; NCV: normalized neocortex volume; NGMV: normalized gray matter volume; NWMV: normalized white matter volume.
P 1: P value in total group analysis between patients with ALS and normal controls, by using two-sample t-test.
P 2: P value in total group analysis between patients with ALS and normal controls, by using analysis of covariance, with age as covariate.