Table 1.
Adult parasite recovery and female worm fecundity from control and Bm-iPGM immunized Mastomys.
| Animal groups | Number of animals | Adult parasite counts/animal | Adult worm recovery (mean ± S.E.) | % reduction in worm burden | % female parasite sterilization | |||
|---|---|---|---|---|---|---|---|---|
| Day 30 p.c. | Day 180 p.c. | Day 30 p.c. | Day 180 p.c. | Day 30 p.c. | Day 180 p.c. | Day 180 p.c. | ||
| PBS | 6/6 | 30, 27, 32, 28, 18, 24 | ♀24, 25, 15, 14, 21, 20 ♂9, 7, 8, 8, 9, 5 |
26.50 ± 2.02 | 27.50 ± 1.95 | 0.0 | 0.0 | 18.50 |
|
| ||||||||
| Adjuvant | 6/6 | 18, 22, 26, 27, 23, 31 | ♀22, 19, 18, 12, 21, 15 ♂13, 10, 11, 8, 11, 10 |
24.50 ± 1.83 | 28.33 ± 2.15 | 7.54 | −3.01 | 20.51 |
|
| ||||||||
| Bm-iPGM | 6/6 | 8, 8, 10, 5, 9, 12 | ♀6, 9, 6, 7, 4, 5 ♂4, 3, 3, 2, 6, 2 |
8.66 ± 0.95*** | 9.5 ± 0.67*** | 67.29 | 65.45 | 69.97 |
Statistically significant values were obtained in Bm-iPGM immunised groups as compared to the control groups. ***P < 0.001. Values represented are mean ± S.E.