Table 1.
Summary of the patients' data.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
|---|---|---|---|---|---|
| Presenting symptoms | Dyspnea | Syncope | Dyspnea | Dyspnea | Dyspnea |
|
| |||||
| Source of thrombus | DVT | DVT | DVT | Unknown | Unknown |
|
| |||||
| Pro-BNP (pg/mL) | 6853 | 149 | 1193 | 7511 | 603 |
|
| |||||
| Troponins (ng/mL) | 1.09 | 0.02 | 0.02 | 0.02 | 0.02 |
|
| |||||
| D-Dimer (ng/mL) | 4060 | 5000 | N/A | N/A | 2072 |
|
| |||||
| CT-scan findings | Right middle and lower lobe emboli | Saddle emboli | Bilateral emboli within main pulmonary arteries | Bilateral emboli within main pulmonary arteries | Saddle emboli |
|
| |||||
| Echocardiogram (RVSP in mmHg) | Hypokinetic RV enlargement (75), RV/LV > 1 | Markedly dilated and hypokinetic RV (70), RV/LV > 1 | RV/LV > 1, severe pulmonary hypertension (73), and hypokinetic RV | Right ventricular strain, straightening of the septum (57), RV/LV > 1 | Hypokinesia of right ventricular free wall (60), RV/LV > 1 |
|
| |||||
| Alteplase amount (per PA) | 12 | 10 | 13 | 12 | 6 |
|
| |||||
| Follow-up echocardiogram (RVSP in mmHg) | Improved function of the right ventricle (50), RV/LV < 1 | Mild RV dyskinesia (62), RV/LV < 1 | No RV strain or pulmonary hypertension (35), RV/LV < 1 | Mildly depressed RV function (40), RV/LV < 1 |
Resolution of RV hypokinesia (45), RV/LV < 1 |
|
| |||||
| Presenting symptoms at the time of discharge | Resolved | Resolved | Resolved | Resolved | Resolved |
DVT = deep vein thrombosis; BNP = brain-natriuretic peptide; sPAP = systolic pulmonary artery pressure during right heart catheterization; RV = right ventricle; LV = left ventricle; PA = pulmonary artery; RVSP = right ventricular systolic pressure.