Table 4. Multivariate Analysis of Pregnancy and Labor/Delivery Complications in Relation to Lymphoma Risk Among California Children Age 0-5 Diagnosed Between 1988 and 2007.
| Controls | Lymphoma cases, total | ||
|---|---|---|---|
| N/ N total* | N/ N total* | OR† (95% CI) | |
| Years collected 2006+ | |||
| Epidural | 2980/7780 | 6/14 | 0.85 (0.27, 2.68) |
| 1989-2005 | |||
| Premature labor | 4169/174962 | 10/384 | 1.15 (0.62, 2.17) |
| Amniocentisis | 4158/174962 | 6/384 | 0.68 (0.30, 1.53) |
| Tocolysis | 1536/174962 | 7/384 | 2.24 (1.06, 4.75) |
| Febrile (> 100 F) | 2052/174962 | 6/384 | 1.40 (0.62, 3.14) |
| 1989+ | |||
| Previous pre-term birth | 2013/182742 | 9/398 | 2.22 (1.14, 4.32) |
| Pre-eclampsia | 3897/182742 | 6/398 | 0.73 (0.33, 1.63) |
| Prolonged labor (> 20 hours) | 1380/182742 | 5/398 | 1.73 (0.71, 4.18) |
| Premature rupture of membrane | 3505/182742 | 10/398 | 1.38 (0.73, 2.58) |
| Induction of labor | 16921/182742 | 29/398 | 0.80 (0.56, 1.18) |
| Stimulation of labor | 18144/182742 | 38/398 | 0.97 (0.69, 1.36) |
| Moderate/heavy meconium staining of amniotic fluid | 7629/182742 | 22/398 | 1.39 (0.90, 2.13) |
| All study years | |||
| Small for gestational age | 20564/196525 | 46/454 | 1.04 (0.75, 1.45) |
| Large for gestational age | 20653/196525 | 59/454 | 1.17 (0.85, 1.62) |
| Preterm birth | 20118/196960 | 45/455 | 0.88 (0.62, 1.26) |
| 1986-2005 | |||
| Fetopelvic disproportion | 4803/200235 | 17/464 | 1.93 (1.15, 3.24) |
| Breech or other abnormal presentation | 5944/200235 | 12/464 | 0.73 (0.36, 1.47) |
| Fetal distress | 6308/200235 | 12/464 | 0.86 (0.46, 1.62) |
| All study years | |||
| Low birth weight | 12119/207549 | 26/477 | 0.87 (0.55, 1.37) 1.37) |
| High birth weight | 22114/207549 | 67/477 | 1.24 (0.92, 1.68) |
| Previous still birth | 3008/207687 | 9/478 | 1.31 (0.62, 2.78) |
The total sample sizes reflected in each row may be smaller than the total number of subjects due to collection of some variables during only a subset of study years
ORs are adjusted for birth year, maternal age and race, and prenatal payment source