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. 2014 Jul 9;13:263. doi: 10.1186/1475-2875-13-263

Table 5.

Transmission-blocking activities of human mAb fed three days post-infected blood meala

Sample Mean oocb PIm[o]c p-valued Mosquitoe PIp[o]f p-valueg Mean Spzh PIm[s]i
MAL1C
15.1
2
0.97
1/20
-27
0.08
9.0
53
 
(0, 36)
(-185, 65)
 
 
(-80, 3)
 
 
 
MAL2A
11.6
24
0.64
1/20
-27
0.08
19.8
-4
 
(0, 30)
(-119, 74)
 
 
(-80, 3)
 
 
 
Contl
15.3
N/A
N/A
5/20
N/A
N/A
19.0
N/A
  (0, 44)              

aAll mAb were tested at 0.231 mg/ml and fed three days post-infected blood meal.

bArithmetic mean (range) of oocysts per mosquito midgut.

cPer cent inhibition of mean oocyst intensity (PIm[o]) and the 95% confidence interval (95% CI).

dTwo-sided p-values for testing whether PIm[o] is significantly different from 0.

eNumber of mosquitoes without any oocysts/number of mosquitoes examined.

fPer cent inhibition of prevalence of mosquitoes with oocysts (PIp[o]) and the 95% CI.

gp-values of PIp[o].

hNumber of sporozoites (×103) per mosquito calculated from a pool of salivary glands of 12 mosquitoes.

iPer cent inhibition of mean sporozoite intensity (PIm[s]).