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. Author manuscript; available in PMC: 2015 May 30.
Published in final edited form as: Vaccine. 2014 Apr 13;32(26):3187–3197. doi: 10.1016/j.vaccine.2014.04.002

Table 5.

Statistical comparison of histopathological scores for the CNS of NHPs inoculated with WNV, WN/DEN4Δ30, DEN4Δ30, or YF 17D virus

Dpi CNS region Virus 1 Virus 2 MG/ND
CI
Difference in mean score* P value Difference in mean score* P value
7 Spinal cord WNV WN/DEN4Δ30 1.6 0.032
7 Spinal cord WNV DEN4Δ30 1.6 0.032
7 Spinal cord WNV YF 17D 1.6 0.032
9/10 Cerebellum WNV WN/DEN4Δ30 3.5 <0.0001 3.6 <0.0001
9/10 Cerebellum WNV DEN4Δ30 2.5 0.0004 2.5 0.011
9/10 Cerebellum WNV YF 17D 3.0 0.0001 3.0 0.0002
9/10 Spinal cord WNV WN/DEN4Δ30 2.9 <0.0001
9/10 Spinal cord WNV DEN4Δ30 2.2 <0.0001
9/10 Spinal cord WNV YF 17D 2.2 <0.0001
*

Positive number indicates that the mean score for the group of animals inoculated with Virus 1 was significantly higher than the mean score for the groups of animals inoculated with Virus 2. Only statistically significant differences are shown.