TABLE 2.

Morbidity in patients undergoing extensive cytoreductive surgery

	Comparison group (n = 222)	Extensive CRS (n = 60)	p value
Intraoperative complications	3 (1.4 %)	1 (1.7 %)	1.0
Overall morbidity	130 (58.6 %)	42 (70 %)	0.1
Grade 3–4 morbidity	51 (23.0 %)	19 (31.7 %)	0.2
60-day mortality	2 (0.9 %)	1 (1.7 %)	0.1
Specific complications, grade ≥3
Delayed gastric emptying	35 (15.8 %)	4 (6.7 %)	0.09
Surgical site infection,  superficial	30 (13.5 %)	9 (15.0 %)	0.8
Surgical site infection, deep	19 (8.6 %)	6 (10 %)	0.8
Pulmonary insufficiency	15 (6.8 %)	6 (10.0 %)	0.4
Ileus >21 days	11 (5.0 %)	5 (8.3 %)	0.3
Sepsis	5 (2.2 %)	2 (3.3 %)	0.6
Anastomotic leak	4 (1.8 %)	2 (3.3 %)	0.6
Thromboembolic event	4 (1.8 %)	0 (0 %)	0.6
Renal insufficiency	2 (0.9 %)	1 (1.7 %)	0.1
Enterocutaneous fistula	1 (0.5 %)	0 (0 %)	1.0
Pancreatic leak	1 (0.5 %)	0 (0 %)	1.0
Biliary leak	1 (0.5 %)	0 (0 %)	1.0
Cardiac event	1 (0.5 %)	3 (5.0 %)	0.03
Hemorrhage	0 (0 %)	3 (5.0 %)	0.009
ICU length of stay, days,  median (IQR)	2 (1–4)	3 (2–4)	0.006
Time to regular diet, days,  median (IQR)	7 (6–10)	9.5 (8–12)	0.0006
Reoperation	7 (3.2 %)	5 (8.3 %)	0.1
Hospital length of stay,  median (IQR)	11.5 (9–15)	14.5 (12–18)	0.0008
Hospital readmission	29 (13.1 %)	10 (16.7 %)	0.5

IQR interquartile range