Table 2.

Hazard ratios (HR) for death with multiple adjustments for all variables shown in Cox proportional Hazards Models at 5 and 13 years.

Variables	Hazard Ratio (95% CI) at 5 years	P value	Hazard Ratio (95% CI) at 13 years	P value
MCI subtypes
Cognitively unimpaired‡	1	0.34	1	<.01
Non-amnestic	1.12 (0.78–1.44)	0.71	1.19 (1.05–1.36)	<.01
Amnestic-single domain	1.06 (0.76–1.48)	<.01	1.31 (1.10–1.56)	<0.001
Amnestic-multiple domain	1.59 (1.13–2.24)		1.67 (1.38–2.02)
Age	1.07 (1.05–1.09)	<0.001	1.09 (1.08–1.10)	<0.001
Gender
Women‡	1	<0.001	1	<0.001
Men	2.70 (2.20–3.32)		2.20 (1.97–2.45)
Education
≥ Primary studies‡	1	<.05	1	0.72
Little or no formal education (≤ 5 years)	0.82 (0.68–0.99)		0.98 (0.88–1.08)
Comorbidity Index *	1.17 (1.11–1.23)	<0.01	1.13 (1.10–1.16)	<0.001

A hazard ratio of less than 1.00 represents a decreased likelihood of death, whereas a hazard ratio greater than 1.00 represents an increased likelihood of death.

^‡This group served as the reference category.

^*Hazard ratio for each disease included (additive effect for each disease).

CI = Interval of Confidence. MCI = Mild Cognitive Impairment.