Table 6.
Unadjusted and adjusted associations between retinal vasculature measurements and incident reported hypertension or use of hypertensive treatment at baseline, participants without ocular opportunistic infections*
Unadjusted | Adjusted** | |||
---|---|---|---|---|
Hazard Ratio |
(95% CI) | Hazard Ratio |
(95% CI) | |
Central Retinal Artery Equivalent | ||||
1st vs. 4th quartile | 2.28 | (1.63 – 3.21) | 2.87 | (1.86 – 4.42) |
2nd vs. 4th quartile | 1.53 | (1.07 – 2.17) | 2.06 | (1.36 – 3.13) |
3rd vs. 4th quartile | 1.56 | (1.09 – 2.22) | 1.73 | (1.17 – 2.57) |
Central Retinal Vein Equivalent | ||||
1st vs. 4th quartile | 1.11 | (0.81 – 1.52) | 0.80 | (0.53 – 1.21) |
2nd vs. 4th quartile | 0.94 | (0.68 – 1.31) | 0.83 | (0.56 – 1.22) |
3rd vs. 4th quartile | 0.87 | (0.62 – 1.21) | 0.83 | (0.57 – 1.22) |
n = 938 participants without ocular opportunistic infection or baseline hypertension and with available retinal vasculature measurements
Adjusted for demographics (age, sex, race, education, insurance status, employment status, weight), HIV characteristics and treatment (HIV risk factor. Time since AIDS diagnosis, CD4+ T-cells: baseline and nadir, HIV viral load: baseline and peak, HAART, PI-based HAART, NNRTI-based HAART) and comorbidities (hyperlipdemia, diabetes and hepatitis C infection: cleared and chronic)