Table 4.
Treatment strategies of orbital LCH.
| Treatment | Type of LCH | References |
|---|---|---|
| observation | LCH, diagnosed elsewhere (sequential multifocal LCH) | 67 |
| incisional biopsy (w/o curettage) | unisystem, unifocal LCH | 68, 69 |
| biopsy and curettage/complete excision | unisystem, unifocal LCH | 18, 20, 45, 46, 72 |
| subtotal curettage and intralesional methylprednisolone (30–125 mg) | unisystem, unifocal LCH (recurrence - 1 case report) | 27, 45, 52 |
| radiation (400–800cGy ) | unisystem, unifocal LCH | 27, 45, 46 |
| chemotherapy (various combinations of prednisone, vinblastine, etoposide, methometrexate, 2-cda, 6-mercaptopurine) | unisystem, unifocal LCH with contact to the Dura Mater multifocal/multisystem LCH recurrent disease | 19, 66, 71, 72, 77 |
| surgical excision, radiation & chemotherapy | single report of “aggressive” LCH | 73 |