Table 2.

Toxicities in patients receiving any protocol therapy (N=14)

Grade toxicity	Number of patients with Grade 1 toxicities	Number of patients with Grade 2 toxicities	Number of patients with Grade ≥3 toxicities
Injection site erythema	5	0
Fatigue	3	0
Flu-like symptoms	1	0
Pain			1*
Myalgias	1	0
Anorexia	2	0
Nausea	2	0
Leukocytosis	2	2
Neutrophilia		1
Eosinophilia	1	1
Dyspnea		1
Tachycardia		1
Chest pain		1
Myocardial infarction			1*

⁺9 patients received all 6 doses without GM-CSF, 3 patients received GM-CSF with 0,2 and 5 doses of vaccine, 2 patients received 1–2 doses of vaccine without GM-CSF;

^*1 death from myocardial infarction occurred following GM-CSF and was considered possibly from therapy (the patient did not receive the peptide); this patient also had generalized pain and myalgias after GM-CSF injection