Table 1.
Clinicopathologic Variables and MAPK/ERK expression
| Categories | SPRY2
 pMEK
 (n=4) |
SPRY2
pMEK
(n=10) |
SPRY2
pMEK
(n=8) |
SPRY2
pMEK
(n=8) |
p Value |
|---|---|---|---|---|---|
| Female (%) | 1 (25) | 7 (70) | 4 (50) | 6 (75) | 0.16 |
| Multifocal (%) | 1 (25) | 6 (60) | 6 (75) | 5 (63) | 0.18 |
| Bilateral (%) | 1 (25) | 5 (50) | 5 (63) | 4 (50) | 0.11 |
| Extrathyroidal extension (%) | 0 (0) | 5 (50) | 4 (50) | 3 (38) | 0.12 |
| Vascular Invasion (%) | 1 (25) | 8 (80) | 8 (100) | 4 (50) | 0.09 |
| Positive Lymph Nodes (%) | 0 (0) | 7 (70) | 8 (100) | 5 (63) | 0.01 |
| Age | 28.5 | 38.2 | 32.7 | 58.4 | 0.01 |
| Size (mm) | 18.5 | 16.0 | 17.3 | 19.8 | 0.85 |