Figure 2.

Plasma efavirenz (EFV) concentrations by CYP2A6 -48T→G genotype. On each graph, each marker represents a different subject. Panels represent all subjects (top left) and self-identified Black subjects (top right), White subjects (bottom left) and Hispanic subjects (bottom right). All have a CYP2B6 slow metabolizer genotype (i.e. 516TT, 516T/983C or 983CC). Genotypes for CYP2A6 -48T→G (rs28399433) are shown. Each marker represents the median of at least two log₁₀-transformed efavirenz determinations on plasma samples obtained 8–19 h post-dose. Horizontal bars are medians and IQRs. Median values are shown below the markers.