Table 2.

Association between SHP2 expression and clinicopathological parameters

Clinicopathologic parameter	SHP2 positive		SHP2-negative		p value
Mean ± SD of tumor size (mm)	30.2 ± 16.4		31.1 ± 19.1		0.3830
Mean ± SD of age at diagnosis (years)	63.8 ± 14.1		63.2 ± 13.7		0.8113
Tumor size	(n)	(%)	(n)	(%)	0.0008
pT1	169	43.9	216	56.1
pT2	360	48.8	377	51.1
pT3	32	29.9	75	70.9
pT4	90	52.3	82	47.7
Lymph node involvement					0.0263
pN0	327	45.1	398	54.9
pN1	245	45.4	294	54.5
pN2	77	57.5	57	42.5
Tumor grade					0.0269
1	134	41.5	189	58.5
2	262	45.5	314	54.5
3	255	50.8	247	49.2
Estrogen receptor					0.1970
ER+	474	45.62	565	54.38
ER−	176	49.58	179	50.42
HER2					0.2207
HER2+	133	49.81	134	50.19
HER2−	515	45.66	613	54.34
Ki67					0.5200
1–14%	169	56.71	129	43.29
15–23%	164	54.30	138	45.70
24–34%	164	50.77	159	49.23
>34%	244	53.39	213	46.61