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Association between SHP2 expression and breast cancer intrinsic subtype
| Intrinsic subtype | SHP2-positive | SHP2-negative | p-value | ||
|---|---|---|---|---|---|
| (n) | (%) | (n) | (%) | 0.9108 | |
|
Luminal A (ER+ and/or PR+, HER2−, Ki-67 < 14%) |
98 | 45.2 | 119 | 54.8 | |
|
Luminal B (HER2-negative) ER+ and/or PR+, HER2−, Ki-67 ≥ 14%) |
307 | 44.9 | 376 | 55.1 | |
|
Luminal B (HER2-positive) (ER+ and/or PR+, HER2+) |
74 | 47.9 | 82 | 52.6 | |
| HER2 type (ER−, PR−, HER2+) | 59 | 53.1 | 52 | 46.8 | |
| Basal-like (ER−, PR−, HER2−) | 110 | 48.5 | 117 | 51.5 | |
