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. 2014 Jul 16;9(7):e101223. doi: 10.1371/journal.pone.0101223

Figure 3. Selective effects of binge ethanol exposure on brain AQP4 and PARP-1 levels in vivo.

Figure 3

Significant elevations over respective controls (C) in levels of AQP4 and PARP-1 in those brain regions selectively incurring neurodamage due to binge ethanol (E) treatment in adult male rats for 4 days (Majchrowicz model). Fig. 3A: Significantly increased AQP4 levels in the HC, EC and OB, but not in CB and FC. Fig. 3B: Significantly increased PARP-1 levels in the HC, EC and OB, but not in CB and FC. *p<0.05 vs. C. n = 4–7 rats/group.