Skip to main content
. 2014 Jun 23;53(27):4368–4380. doi: 10.1021/bi500219t

Table 1. Thermal Stability of MftR and Mutants.

    6 μM urate 100 μM urate mftrO mftpO
MftR D1 49.4 ± 0.3 49.2 ± 0.2 61.3 ± 1.0 53.0 ± 0.2 52.7 ± 0.2
MftR D2 57.9 ± 0.1 58.0 ± 0.1 60.3 ± 0.1 60.9 ± 0.3
W11F 24.7 ± 0.1 27.0 ± 0.1 28.8 ± 0.7 a a
D56S 50.5 ± 0.2 52.3 ± 0.3 51.3 ± 0.1 48.4 ± 0.1 48.0 ± 0.1
R63S 43.0 ± 0.1 48.7 ± 0.4 64.1 ± 3.9 42.8 ± 0.2 43.0 ± 0.2
R89N 53.0 ± 0.2 55.9 ± 0.2 63.0 ± 0.6 54.0 ± 0.1 55.6 ± 0.9
a

Did not yield quantifiable data.