Table 2. Binding Affinity and Inhibition Constant of MftR and Variants.
| Kd (nM) | nH | IC50 (mM) | |
|---|---|---|---|
| MftR | 1.6 ± 0.1 | 0.8 ± 0.1 | 3.0 ± 0.1 |
| W11F | 6.3 ± 0.5 | 0.6 ± 0.2 | 5.9 ± 0.8 |
| D56S | 220.0 ± 1.8 | 0.7 ± 0.1 | 3.1 ± 0.1 |
| R63S | 15.1 ± 1.3 | 0.9 ± 0.1 | 8.0 ± 0.2 |
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