Table I.
Vehicle
|
8 μg/kg PTH
|
40 μg/kg PTH
|
||||
---|---|---|---|---|---|---|
C (n = 19) | D (n = 17) | C (n = 13) | D (n = 12) | C (n = 14) | D (n = 15) | |
|
|
|
||||
Non-fasting glucose (mg/dl) | 173 ± 8 | 491 ± 27* | 151 ± 9@ | 531 ± 14* | 164 ± 13 | 534 ± 19* |
Body mass (g) | 27.9 ± 0.4 | 25.5 ± 0.5* | 28.6 ± 0.4 | 25.6 ± 0.6* | 29.0 ± 0.5 | 26.3 ± 0.5* |
Tibialis anterior (mg) | 50 ± 1 | 42 ± 3* | 52 ± 1 | 43 ± 1* | 52 ± 1 | 43 ± 1* |
Femoral fat pad (mg) | 133 ± 5 | 78 ± 7* | 112 ± 8^ | 76 ± 6* | 114 ± 9@ | 75 ± 6* |
Perirenal fat pad (mg) | 37 ± 3 | 16 ± 2* | 31 ± 3@ | 16 ± 2* | 32 ± 4 | 14 ± 2* |
Marrow adipocyte #/mm2 § | 7 ± 1 | 20 ± 3* | 12 ± 2^ | 23 ± 7* | 9 ± 3 | 17 ± 3* |
Abbreviations: C, control; D, diabetic; PTH, parathyroid hormone, no., number.
Significance:
p < 0.05 compared treatment-matched control.
p < 0.05 compared to vehicle treated control.
p < 0.1 compared to vehicle treated control, by t-test.
n = 4–12 per group.