Table 1. Comparison of demographics, clinical characteristics, underlying diseases of NH-PCP and HIV-PCP patients.
Characteristics | NH-PCP (n = 46) | HIV-PCP (n = 105) | P-Value |
Demographics | |||
Age, years | 54.67±14.40 | 37.51±9.41 | <0.001 |
Male gender | 28 (60.9) | 98 (93.3) | <0.001 |
Patients according to underlying diseases | |||
Transplant recipients | 12 (26.09) | - | |
Connective tissue diseases | 11 (23.91) | - | |
Hematological diseases | 5 (10.87) | 1 (0.95) | |
Malignant hematological diseases | 5 (10.87) | - | |
Benign hematological diseases | - | 1 (0.95) | |
Solid tumor | 4 (8.70) | - | |
Nephrotic syndrome | 5 (10.87) | - | |
Chronic pulmonary diseases | 4 (8.70) | - | |
Other conditions | 5 (10.87) | - | |
Symptomology and clinical presentation | - | ||
Cough | 37 (80.4) | 79 (75.2) | 0.49 |
Dyspnea | 36 (78.3) | 84 (80.0) | 0.81 |
Fever | 41 (89.1) | 95 (90.5) | 0.78 |
Chest pain | 3 (6.5) | 14 (13.3) | 0.22 |
Loss of weight | 12 (26.1) | 65 (61.9) | <0.001 |
Pneumothorax | 2 (4.3) | 4 (3.8) | 1.00 |
Laboratory results | |||
Hgb, g/L | 116.00±25.69 | 119.69±22.02 | 0.37 |
Lymphopenia,% | 32 (69.6) | 71 (67.6) | 0.81 |
TP,g/L | 56.63±8.67 | 72.07±9.54 | <0.001 |
ALB,g/L | 26.75±6.20 | 31.96±5.63 | <0.001 |
LDH,u/L | 338.00 (175.00–531.00) | 297.80 (188.50–879.00) | 0.80 |
Pct(n = 37/54),ng/ml | 0.14 (0.05–17.18) | 0.08 (0.05–62.37) | 0.71 |
CRP (n = 34/98),mg/dl | 21.62 (0.19–160.00) | 53.30 (1.30–260.40) | <0.001 |
ESR (n = 39/100),mm/h | 33.85±19.95 | 62.92±28.00 | <0.001 |
CD4 T cell count (n = 27/92),cells/µl | 182.00 (17.00–847.00) | 22.00 (2.00–151.00) | <0.001 |
CD8 T cell count (n = 27/92),cells/µl | 224.00 (29.00–484.00) | 411.00 (76.00–1017.00) | <0.001 |
CD4/CD8 (n = 27/92),% | 1.51 (0.1–3.69) | 0.05 (0.01–0.38) | <0.001 |
Data are presented as medians (range) or numbers (%) or mean ± SD, as appropriate. ALB = albumin; CRP = C-reactive protein; ESR = erythrocyte sedimentation rate; Hgb = hemoglobin; LDH = lactate dehydrogenase; Pct = procalcitonin; TP = total protein.