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. 2014 Jul 16;9(7):e101943. doi: 10.1371/journal.pone.0101943

Table 1. Comparison of demographics, clinical characteristics, underlying diseases of NH-PCP and HIV-PCP patients.

Characteristics NH-PCP (n = 46) HIV-PCP (n = 105) P-Value
Demographics
Age, years 54.67±14.40 37.51±9.41 <0.001
Male gender 28 (60.9) 98 (93.3) <0.001
Patients according to underlying diseases
Transplant recipients 12 (26.09) -
Connective tissue diseases 11 (23.91) -
Hematological diseases 5 (10.87) 1 (0.95)
 Malignant hematological diseases 5 (10.87) -
 Benign hematological diseases - 1 (0.95)
Solid tumor 4 (8.70) -
Nephrotic syndrome 5 (10.87) -
Chronic pulmonary diseases 4 (8.70) -
Other conditions 5 (10.87) -
Symptomology and clinical presentation -
Cough 37 (80.4) 79 (75.2) 0.49
Dyspnea 36 (78.3) 84 (80.0) 0.81
Fever 41 (89.1) 95 (90.5) 0.78
Chest pain 3 (6.5) 14 (13.3) 0.22
Loss of weight 12 (26.1) 65 (61.9) <0.001
Pneumothorax 2 (4.3) 4 (3.8) 1.00
Laboratory results
Hgb, g/L 116.00±25.69 119.69±22.02 0.37
Lymphopenia,% 32 (69.6) 71 (67.6) 0.81
TP,g/L 56.63±8.67 72.07±9.54 <0.001
ALB,g/L 26.75±6.20 31.96±5.63 <0.001
LDH,u/L 338.00 (175.00–531.00) 297.80 (188.50–879.00) 0.80
Pct(n = 37/54),ng/ml 0.14 (0.05–17.18) 0.08 (0.05–62.37) 0.71
CRP (n = 34/98),mg/dl 21.62 (0.19–160.00) 53.30 (1.30–260.40) <0.001
ESR (n = 39/100),mm/h 33.85±19.95 62.92±28.00 <0.001
CD4 T cell count (n = 27/92),cells/µl 182.00 (17.00–847.00) 22.00 (2.00–151.00) <0.001
CD8 T cell count (n = 27/92),cells/µl 224.00 (29.00–484.00) 411.00 (76.00–1017.00) <0.001
CD4/CD8 (n = 27/92),% 1.51 (0.1–3.69) 0.05 (0.01–0.38) <0.001

Data are presented as medians (range) or numbers (%) or mean ± SD, as appropriate. ALB  =  albumin; CRP  =  C-reactive protein; ESR  =  erythrocyte sedimentation rate; Hgb  =  hemoglobin; LDH  =  lactate dehydrogenase; Pct  =  procalcitonin; TP  =  total protein.