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. 2014 Jul 16;9(7):e101943. doi: 10.1371/journal.pone.0101943

Table 2. Characteristics associated with mortality in a univariate Cox regression analysis in patients with PCP.

Unadjusted HR(95% CI) P-value Unadjusted HR(95% CI) P-value
Age, years 1.03 (0.97–1.09) 0.40 1.04 (0.99–1.09) 0.10
Gender, male 1.22 (0.27–5.43) 0.80 0.05 (0.00–518.81) 0.51
oxygenation index≤300 69.19 (0.16–30395.79) 0.17 4.11 (1.34–12.57) 0.01
Neu%≥85% 6.75 (0.81–56.11) 0.08 7.32 (2.25–23.81) 0.001
Lym%≤10% 62.96 (0.14–27618.67) 0.18 3.88 (1.27–11.86) 0.02
ALB≤25 g/L 2.39 (0.53–10.66) 0.26 2.39 (0.66–8.69) 0.19
ALB≤30 g/L 42.84 (0.07–24998.30) 0.25 3.44 (1.06–11.17) 0.04
Pct≥0.5 ng/ml 9.37 (1.81–48.44) 0.008 19.34 (5.30–70.57) <0.001
CD4 cell count≤50 cells/µl - - 4.89 (0.64–37.58) 0.13
four or more clinical manifestations (cough, dyspnea, fever, chest pain, and weight loss) 14.31 (1.72–119.18) 0.01 1.08 (0.36–3.22) 0.89
Coinfection 13.36 (1.61–111.12) 0.02 0.82 (0.25–2.68) 0.75
Admission to ICU 11.99 (1.44–99.74) 0.02 52.71 (11.55–240.52) <0.001
Mechanical ventilation 110.98 (0.19–63845.43) 0.15 91.90 (11.88–711.12) <0.001
Time from admission to initial treatment, days 1.05 (0.99–1.12) 0.08 1.01 (1.00–1.02) 0.02

ALB  =  albumin; CI  =  confidence interval; HR  =  hazard ratio; ICU  =  intensive care unit; Lym  =  lymphocyte; Neu  =  neutrophil; Pct  =  procalcitonin.