Table 2. Estimated QTL effects for apoptotic cell fraction (ACF). Results for the multiple QTL additive model are shown, including additive and dominance effects for each QTL.
| LG | QTL, cMǂ | LOD | %Var.† | F | P-val.ˆ | BayesInt‡ | Additive (se)ˇ | Dominance (se)ˇ | Peak marker˚ |
|---|---|---|---|---|---|---|---|---|---|
| Additive | |||||||||
| 4 | 43 | 8.4 | 11.9 | 3.8 | *** | 0.0-57.3 | 0.00(0.06) | 0.22(0.08) | ERG28 |
| 10 | 33 | 5.7 | 7.1 | 4.18 | *** | 24.1-40.6 | 0.16 (0.11) | 0.35(0.15) | HECTD3 |
| 15 | 24 | 5.4 | 5.7 | 3.7 | ** | 19.2-28.3 | 0.06(0.09) | 0.05 (0.13) | PHPT1 |
| 6 | 45 | 2.1 | 2.9 | 4.5 | * | 21.1-55.7 | −0.15(0.05) | −0.09(0.08) | PHB |
| 7 | 2 | 0.9 | 1.2 | 0.65 | * | 0.0-105.2ˇ | 0.02 (0.06) | 0.16 (0.08) | GSHR |
| Interaction | a:a | d:d | a:d | d:a | |||||
| 10:4 | 56:43 | 6.7 | 7.0 | 5.5 | *** | 0.01(0.13) | −0.01(0.33) | 0.35(0.16) | 1.07(0.23) |
LG, linkage group
ǂ
position of QTL in centimorgan
†
variance explained by QTL in F2 phenotype
‡
Bayes confidence intervals (Manichaikul et al. 2006)
˚
Marker nearest to the cM position at which the greatest F-value was observed
ˆ
P values of the F-statistic: ‘***’< 0.001, ‘**’< 0.01, ‘*’< 0.05
ˇ
Additive (a) and dominance (d) effects with standard error in parentheses calculated from ln-transformed values, and direction shown as N. kadleci allele effect. Effect interactions are shown with (:)