Figure 8.

(A) SB rescued the cell proliferation of H₂O₂-treated hMESCs. Cell number was determined daily by FACS (M ± SD, N = 3, **p<0.005, ***p<0.001, versus control, §p<0.05, versus H₂O₂-treated cells). (B) SB partially prevented H₂O₂-induced increase of cell size. Forward scatter (FS) reflects the average cell size. M ± SD, N = 3, *p<0.05, **p<0.005, versus control, §p<0.05, §§<0.005, versus H2O2-treated cells. (C) Inhibition of p38 activity had no effect on long-term activation of pp53 or (D) p21. (E) An impact of inhibition of p38 kinase activity on pRb phosphorylation status.