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. 2014 Jul 16;9(7):e102521. doi: 10.1371/journal.pone.0102521

Figure 4. Representative gene array analysis for angiogenesis-related genes of IECs cultured in different experimental conditions.

Figure 4

A–B) Results are expressed as fold-variation of pro-angiogenic and anti-angiogenic genes of IECs cultured for 12 hrs (gray columns) or 24 hrs (black columns) with EVs or with vehicle alone. Samples were normalized for signals generated by housekeeping genes (Actin, GAPDH). Three independent experiments were performed with similar results. Gene table: AKT1, Angipoietin1, CXCL 1, Ephrin A3, Fibroblast Growth Factor Receptor 3, Vascular Endothelial Growth Factor Receptor 1, HAND 2, Jagged 1, Leptin, MDK, Neuropilin 2, TIE 2, Angiopoietin 2, BAI 1, Endostatin, Tumstatin, CXCL 10, Notch 4, Thrombospondin 1, Tissue Inhibitor of metallo proteinases 1 and 2.