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. 2014 Jul 16;9(7):e102876. doi: 10.1371/journal.pone.0102876

Figure 3. Morphological changes caused by different high-fat diets.

Figure 3

(A) SC, standard chow diet produced no prostate alterations; (B) HF-S, a high-fat diet rich in saturated fatty acid (lard) caused an increase in the area density of the connective tissue and the smooth muscle cells; (C) HF-P, a high-fat diet rich in polyunsaturated fatty acid (canola oil) promoted an increase in the area density of the epithelium, the connective tissue and the smooth muscle cells; (D) HF-SP, a high-fat diet rich in saturated and polyunsaturated fatty acids induced an increase in the area density of the lumen, the epithelium, the connective tissue and the smooth muscle cells. The symbol [a] indicates a result that is different from the SC group, [b] indicates a result that is different from the HF-S group and [c] indicates a result that is different from the HF-P group (one-way ANOVA and Bonferroni’s post hoc test, p<0.05). H&E staining and immunostaining for Alpha Smooth Muscle Actin, 200x.