TABLE 4.

P-values for inference on the effects of pre-enhancement positioning on CTp parameter values. Each p-value corresponds to a two-sided test for the absence of deviation in resultant CTp values from the reference set point (T₁=0s) at a given shift from T₁ (T₁ = ±0.5s, ±1.0s, ±2.0s). Boldface values represent statistically significant differences after adjusting for multiple comparisons using Bonferroni’s correction. The Table shows that the pattern of results is essentially the same for 220s and 360s.

Table 4a: 220s acquisition duration

	Tumor						Normal
	−2.0s	−1.0s	−0.5s	0.5s	1.0s	2.0s	−2.0s	−1.0s	−0.5s	0.5s	1.0s	2.0s
BF	0.571	0.942	0.966	0.773	0.781	0.655	0.771	0.898	0.419	0.449	0.416	0.054
BV	0.043	0.091	0.443	0.259	0.084	<0.001	0.002	0.104	0.445	0.114	0.004	<0.001
MTT	<0.001	0.001	0.073	0.046	<0.001	<0.001	<0.001	0.117	0.078	0.121	0.003	<0.001
PS	0.001	0.098	0.448	0.366	0.085	0.004	<0.001	0.022	0.115	0.042	0.008	<0.001
HAF	0.004	0.064	0.374	0.147	0.039	<0.001	0.142	0.134	0.677	0.391	0.047	<0.001

Table 4b: 360s acquisition duration

	Tumor						Normal
	−2.0s	−1.0s	−0.5s	0.5s	1.0s	2.0s	−2.0s	−1.0s	−0.5s	0.5s	1.0s	2.0s
BF	0.544	0.956	0.984	0.766	0.753	0.639	0.726	0.784	0.419	0.444	0.387	0.045
BV	0.042	0.091	0.403	0.300	0.094	<0.001	0.013	0.070	0.511	0.133	0.004	<0.001
MTT	<0.001	0.001	0.045	0.079	<0.001	<0.001	0.004	0.151	0.104	0.066	0.001	<0.001
PS	0.001	0.106	0.459	0.352	0.090	0.003	<0.001	0.030	0.113	0.023	0.003	<0.001
HAF	0.004	0.065	0.348	0.151	0.041	<0.001	0.146	0.110	0.689	0.391	0.050	<0.001