Table 3.

Major Hemorrhage and Thromboembolism Complications

	Manual Alerts	PHS Alerts	P value
Patients, n	3497	3781
PT/INR measurements+	15,790	16,704
PT value > 50, n (%)	583 (4)	444 (3)	< 0.01
Number of complications, event (person)	164 (139)	223 (171)	0.24*
Number of thromboembolic events, event (person)	56 (50)	62 (58)	0.709*
Number of hemorrhagic events, event (person)	108 (96)	161 (123)	0.198*
Major hemorrhage, event (person)	94 (86)	131 (111)
Treatment with vitamin K, event (person)	14 (12)	30 (18)

^* P values calculated by comparing percentage of patients with complications in both study groups

⁺ Only outpatients included