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Comparison of histology and optical spectroscopy end points. The upper two figures show the temporal changes in mean fractions of vital tumor tissue, necrosis, and fibrosis for the control (A) and treated (B) groups, as assessed by histologic staining using HE. The lower two figures (C and D) show temporal changes in the Mie-scattering slope, the Mie-to-total scattering fraction, and the fluorescence residual for both groups. Error bars indicate SE.
