Figure 4.
Relationship between 18F-FDG uptake and hypoxia, proliferation, and perfusion in HT29 serosal carcinomatosis. Hypoxic regions, where pimonidazole, GLUT-1, and CA9 are stained positively, have high 18F-FDG uptake (white arrow). Well-perfused regions where Hoechst 33342 is positive and proliferating cancer cells stained positively for bromodeoxyuridine have low 18F-FDG uptake (red arrow). All scale bars are 2 mm.