Table 4.
Hub genes (degree of nodes ≥ 10) in two-way interactions of WTCCC-BD
Hub gene | degree | location | SNP(s) | Referencea |
---|---|---|---|---|
B3GALT5 | 115 | 21q22.2b | rs980184 | [25] |
LOC442261 | 98 | 6q23.2d | rs4896044 | |
PI15 | 32 | 8q21.11b | rs2954873 | [26] |
LOC390730 | 26 | 16q12.2a | rs7188309 rs11640993 rs8056052 rs2192859 rs1344484 rs10521275 rs11647459 rs2387823 |
[19] |
PHF20 | 24 | 20q11.23a | rs6060710 | |
TLE4 | 13 | 9q21.31b | rs914715 rs11138278 | [27] |
DPP10 | 12 | 2q14.1b | rs11123306 rs708647 rs1375144 rs6741692 | [28,19] |
AKAP10 | 10 | 17p11.2d | rs203466 rs203457 rs119672 rs2108978 | [29] |
CHST2 | 10 | 3q23d | rs4683457 | [30] |
a. Reference is literature related with bipolar disorder.