Table 4.
Approved and clinical targets for seven complex diseases
| PH | AT | NAT | CT | NCT |
|---|---|---|---|---|
| T2D | 45 | 41 | 65 | 62 |
| T1D | 57 | 55 | 73 | 72 |
| HT | 71 | 68 | 43 | 40 |
| RA | 55 | 53 | 59 | 54 |
| CD | 93 | 93 | 135 | 135 |
| CAD | 63 | 61 | 80 | 76 |
| BD | 37 | 36 | 44 | 44 |
| Unique sum | 291 | 277 | 334 | 318 |
Abbreviations - PH - Phenotypes; AT - Approved Targets; NAT - Novel Approved Targets; CT - Clinical Targets; NCT - Novel Clinical Targets; T2D - Type 2 Diabetes; T1D - Type 1 Diabetes; HT - Hypertension; RA - Rheumatoid Arthritis; CD - Crohn's Disease; CAD - Coronary Artery Disease; BD - Bipolar Disorder.
Predicted therapeutic targets targeted by FDA-approved drugs and drugs in clinical trials.