Table 5.
Binary classification of therapeutic targets
| PH | Total genes in all search spaces | Binary classification | |
|---|---|---|---|
| T2D | 4,292 | TP = 7 | FP = 77 |
| FN = 9 | TN = 4,199 | ||
| T1D | 5,339 | TP = 2 | FP = 95 |
| FN = 9 | TN = 5,233 | ||
| HT | 8,427 | TP = 5 | FP = 73 |
| FN = 15 | TN = 8,334 | ||
| RA | 4,970 | TP = 6 | FP = 71 |
| FN = 9 | TN = 4,884 | ||
| BD | 5,667 | TP = 1 | FP = 58 |
| FN = 6 | TN = 5,602 | ||
| CD | 5,644 | TP = 0 | FP = 135 |
| FN = 0 | TN = 5,509 | ||
| CAD | 4,715 | TP = 4 | FP = 98 |
| FN = 8 | TN = 4,605 | ||
Abbreviations - TP - True Positives; FP - False Positives; TN - True Negatives; FN - False Negatives; TN - True Negatives; PH - Phenotypes; T2D - Type 2 Diabetes; T1D - Type 1 Diabetes; HT - Hypertension; RA - Rheumatoid Arthritis; CD - Crohn's Disease; CAD - Coronary Artery Disease; BD - Bipolar Disorder.
Binary classification of therapeutic targets considering targets present in six search spaces from weakly significant data set.