Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 2;4(2):240–272. doi: 10.3390/brainsci4020240

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

PMC Copyright notice

(a) As expected in Study 1 (since the Severe HI subset was selected for cortical atrophy), a t-test on right cortical volume revealed a significant effect of Treatment (* p < 0.05, Severe HI smaller than sham). For Study 2, an ANOVA comparing HI and sham animals revealed a Hemisphere × Treatment interaction, and a t-test also showed a trend (# p = 0.07) for HI to have smaller right cortical volume. Analysis of right cortical volume across Study confirmed a robust overall HI effect (p < 0.05) and a lack of between-study differences. (b) For Study 1, an ANOVA comparing hippocampal volumes in severe HI and sham animals revealed an overall Treatment effect (p = 0.05). A t-test comparing right hippocampal volume in both groups in Study 1 revealed a significant effect of Treatment (* p < 0.05), as was seen in Study 2 (* p < 0.05; HI smaller than sham). Analysis of right hippocampal volume across Study confirmed a robust overall HI effect (p < 0.005), and a lack of between-study differences.