Table 2.

Metabolic parameters in Dahl SS rats

Dahl-SS	Intact-NS (7)	OVX-NS (7)	Intact-HS (7)	OVX-HS (7)
Body weight ratio, g
Baseline	230 ± 6	254 ± 4†	228 ± 4	260 ± 3†
Week 1	249 ± 8	271 ± 6†	244 ± 6	282 ± 6†
Week 2	253 ± 9	280 ± 7†	240 ± 5	280 ± 6†
Food intake, g/day
Baseline	21 ± 1	20 ± 1	21 ± 1	21 ± 1
Week 1	17 ± 1	19 ± 1	17 ± 1	16 ± 1
Week 2	14 ± 1	16 ± 1	14 ± 1	13 ± 1
Water intake, ml/day
Baseline	20 ± 1	16 ± 2	16 ± 1	21 ± 1
Week 1	19 ± 2	20 ± 2	43 ± 3*‡	49 ± 3*‡
Week 2	19 ± 2	20 ± 2	45 ± 3*	44 ± 4*
Urine output, ml/day
Baseline	14 ± 1	11 ± 1	9 ± 1	14 ± 1
Week 1	12 ± 2	19 ± 4	36 ± 3*‡	44 ± 3*‡
Week 2	11 ± 1	15 ± 2	27 ± 3*	37 ± 3*†
Urinary Na+ excretion, mmol/day
Baseline	0.79 ± 0.1	0.78 ± 0.5	0.64 ± 0.1	0.81 ± 0.1
Week 1	0.68 ± 0.1	0.93 ± 0.1	11.28 ± 0.8*‡	11.06 ± 0.1*‡
Week 2	0.69 ± 0.1	0.80 ± 0.1	10.05 ± 0.6*	10.96 ± 0.3*

At baseline, all rats were maintained on phytoestrogen-free NS diet (0.4% NaCl; Harlan Teklad). Rats were then randomized to remain on NS or were switched to phytoestrogen-free HS diet (4% NaCl) for an additional 2 wk. All data are expressed as means ± SE.

^*Significant difference from NS control of the same group (intact or OVX).

^†Significant difference from gonad-intact of the same treatment group (NS or HS).

^‡Significant difference from the previous week within the same group. Numbers in parentheses refer to n values.