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. 2014 May 14;307(2):R198–R205. doi: 10.1152/ajpregu.00101.2014

Fig. 4.

Fig. 4.

A single subordination stress (SSS) episode acutely elevates corticosterone and phase advances the adrenal but not the anterior pituitary PER2Luc rhythm. A: schematic of the experimental procedures. Subordinate mouse (black) undergoes social interaction with dominant mouse (white) for 10 min and then mice are housed together separated by a partition for 8 h. B: corticosterone is elevated 30 min after the single defeat exposure (control, n = 8; SSS, n = 6). C: corticosterone remains elevated after a social defeat followed by 8 h sensory contact (control, n = 4; SSS, n = 5). D: PMT tracing of adrenal samples from representative control and subordinate mice. E: adrenal PER2Luc peak phase is advanced in subordinate mice (control, n = 5; SSS, n = 5). F: PMT tracing of pituitary samples from representative control and subordinate mice. G: pituitary PER2LUC peak phase is not altered in subordinate mice (control, n = 5; SSS, n = 5). *P < 0.05, **P < 0.01, ***P < 0.001.