Table 1.

Protein kinases whose activities are regulated by vasopressin based on previous phosphoproteomics studies

Kinase (Gene Symbol)	Kinase Class	Phosphorylation Site(s)	Phosphorylation Change	Effect on Kinase Activity	Experimental Preparation	Reference No.
Akt1	AGC	S473	Up	Up	Rat IMCD	43
Akt1	AGC	T308	Up	Up	Rat IMCD	43
Camk2b	CAMK	T287	Up	Up	Mouse mpkCCD	45
Camk2d	CAMK	T287	Up	Up	Mouse mpkCCD	45
Gsk3a	CMGC	Y279	Down	Down	Rat IMCD	23
Mapk1	CMGC	T183 and Y185	Down	Down	Rat IMCD	43
Mapk1	CMGC	T183 and Y185	Down	Down	Mouse mpkCCD	45
Mapk14	CMGC	Y182	Down	Down	Rat IMCD	23
Mapk3	CMGC	T203 and Y205	Down	Down	Rat IMCD	43
Mapk3	CMGC	T203 and Y205	Down	Down	Mouse mpkCCD	45
Mapk9	CMGC	T183 and Y185	Down	Down	Rat IMCD	23
Map2k1	STE	S218 and S222	Down	Down	Rat IMCD	43
Map2k2	STE	S222 and 226	Down	Down	Rat IMCD	43
Map2k3	STE	S218	Down	Down	Rat IMCD	23
Map2k5	STE	S311	Down	Down	Rat IMCD	23
Map2k6	STE	S207	Down	Down	Rat IMCD	23
Hck	TK	Y409	Down	Down	Rat IMCD	23
Araf	TKL	S255	Down	Down	Rat IMCD	23
Raf1	TKL	S259	Up	Down	Rat IMCD	43
Raf1	TKL	S29	Up	Down	Rat IMCD	23

IMCD, inner medullary collecting duct; mpkCCD, cortical collecting duct cell line.