Table 2.

Calculated prior probabilities for the top-20 kinases with regard to likelihood of a role in AQP2 phosphorylation at Ser²⁵⁶

			Expression			Regulated by AVP
Rank	Kinase Gene Symbol	Bayes' Probability	Transcript	Protein	Kinase Family	PTM	Ca2+/cAMP
1	Camk2d	0.0452	Yes	Yes	CAMK	Yes and activated	Yes
2	Akt1	0.0251	Yes	Yes	AGC	Yes and activated	No
2	Prkaca	0.0251	Yes	Yes	AGC	Unknown	Yes
2	Prkacb	0.0251	Yes	Yes	AGC	Unknown	Yes
5	Cdc42bpb	0.0181	Yes	Yes	AGC	Yes	Yes
5	Prkcd	0.0181	Yes	Yes	AGC	Yes	Yes
7	Cask	0.0139	Yes	Yes	CAMK	Unknown	No
7	Dapk3	0.0139	Yes	Yes	CAMK	Unknown	No
7	Mark2	0.0139	Yes	Yes	CAMK	Unknown	No
7	Mark3	0.0139	Yes	Yes	CAMK	Unknown	No
7	Nuak2	0.0139	Yes	Yes	CAMK	Unknown	No
7	Pdpk1	0.0139	Yes	Yes	AGC	Unknown	No
7	Pkn1	0.0139	Yes	Yes	AGC	Unknown	No
7	Pkn2	0.0139	Yes	Yes	AGC	Unknown	No
7	Prkci	0.0139	Yes	Yes	AGC	Unknown	No
7	Rock2	0.0139	Yes	Yes	AGC	Unknown	No
7	Rps6ka1	0.0139	Yes	Yes	AGC	Unknown	No
18	Camk1	0.0132	Yes	No	CAMK	Unknown	No
18	Phkg2	0.0132	Yes	No	CAMK	Unknown	No
20	Camkk2	0.0122	Yes	Yes	Other	Yes	No

AQP2, aquaporin-2; PTM, posttranslational modification.