Table 2.
Transport parameters of macula densa cells
Transporter | Value | Unit | Reference |
---|---|---|---|
Na+/H+ exchanger density (apical) | 6 | 10−9 mmol/cm2 | (48) |
Na+-K+-ATPase density | 1,040 | 10−9 mmol/s/cm2 | Estimated |
K+ apical permeability | 40 | 10−5 cm/s | (19) |
K+ basolateral permeability | 0.2 | 10−5 cm/s | Estimated |
Cl− basolateral permeability | 5.0 | 10−5 cm/s | Estimated |
HCO3− basolateral permeability | 0.5 | 10−5 cm/s | Estimated |
Pf, apical membrane | 133 | 10−4 cm/s | (12) |
Pf, tight junction | 700 | 10−4 cm/s | (48) |
Pf, basolateral membrane | 1,687 | 10−4 cm/s | (12) |
Pf, osmotic permeability. Other transport parameters are identical to those of the TAL and are listed in Table 1 in Ref 48.