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Arterial blood lactate (A) and glycerol (C) and plasma nonesterified fatty acid (NEFA; E) concentrations and net hepatic balances of lactate (B), glycerol (D), and NEFA (F) during basal (−20 to 0 min) and experimental periods (0–180 min) of HIHG clamps in CTR (◻), HFA (▲), and HFR (○) diet groups. Data are means ± SE; n = 5/group. *P < 0.05, CTR vs. other groups; **P < 0.05, HFR vs. other groups; †P < 0.05, HFA vs. CTR; ‡P < 0.05, HFR vs. CTR.
