Table 2.
Experimental Period |
|||
---|---|---|---|
Group | Basal Period | Period 1 (−PoG) | Period 2 (+PoG) |
Total glucose infusion rate, mg·kg−1·min−1 | |||
CTR | 0.0 ± 0.0 | 9.0 ± 3.0 | 10.2 ± 2.4 |
HFA | 0.0 ± 0.0 | 5.7 ± 0.8 | 8.4 ± 1.2 |
HFR | 0.0 ± 0.0 | 4.9 ± 0.6 | 8.5 ± 1.2 |
Nonhepatic glucose uptake, mg·kg−1·min−1 | |||
CTR | 1.7 ± 0.2 | 6.8 ± 2.1 | 6.3 ± 2.4 |
HFA | 1.8 ± 0.2 | 5.7 ± 0.6 | 6.4 ± 1.0 |
HFR | 2.0 ± 0.1 | 5.9 ± 0.5 | 7.2 ± 1.0 |
Glucose Rd, mg·kg−1·min−1 | |||
CTR | 2.5 ± 0.2 | 7.1 ± 1.6 | 9.0 ± 2.0 |
HFA | 2.7 ± 0.2 | 6.4 ± 0.5 | 7.7 ± 1.0 |
HFR | 2.6 ± 0.2 | 6.1 ± 0.4 | 7.8 ± 1.0 |
Values are means ± SE; n = 5/group. Rd, glucose disappearance; −PoG, no portal glucose; +PoG, portal glucose infusion. The glucose infusion rate (GIR) during period 2 is the sum of the portal and peripheral GIRs; the portal GIR was 4 mg·kg−1·min−1 in all groups. There were no significant differences among groups.