Fig. 7.

Microvessel alignment relative to the z-axis. Length-normalized distributions of orientation for the hexahedral constructs (A) and cylindrical constructs (B) are shown. The 10° bin represents angles from 0° to 10°, which are parallel to the z-axis of the hexahedral constructs. The 90° bin represents angles from 80° to 90° and is parallel to the XY-plane of the hexahedral constructs. Most of the vessel segments for all of the boundary conditions were parallel to the XY-plane. Significant differences were detected between U and the other groups in the 70°, 80°, and 90° angle bins (*P < 0.01). The unconstrained cultures U and CU were significantly different than the other constrained cultures in all but the 10° and 20° angle bins (*P < 0.05). Bars indicate standard error.