Fig. 5.

Obese mice have a heightened acute inflammatory response to noxious stimuli. A: representative low-power (bottom; ×5 magnification) and high-power (top; ×40 magnification) histological hematoxyalin and eosin-stained sections of lean and obese mice abdominal skin before (0 h) and 12 h after croton oil activation. The short black arrow points to a crown-like structure. B–D: flow plots and quantification of leukocytes (B), macrophages (C), and neutrophils (D) from the abdominal skin of lean and obese mice before (0 h) and 12 h after croton oil application. *P < 0.05.