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Up-regulation of genes encoding the mouse opiorphin homologues A2BR and HIF-1a in corporal tissue of SCD mice prior to physiological evidence of priapism. Expression profiles of mSmr3a, mSmr2, a2br, and Hif-1a in corporal tissue in control and SCD mice at the age of 5 and 12 wk, normalized to the housekeeping gene rpl19. Bars represent mean change in gene expression in SCD mice compared to controls; 5 animals/age group. *P < 0.05 vs. control.
