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. 2014 May 22;307(2):G177–G186. doi: 10.1152/ajpgi.00038.2014

Fig. 2.

Fig. 2.

LR17938 reduced incidence and severity of NEC. A: representative intestinal histological changes in dam-fed, dam-fed + 17938, FS (NEC protocol), and FS + 17938 mice. Ileal tissues were stained with hematoxylin and eosin. Magnification ×200. Red arrows, villous core separations in animals with NEC; black arrows, normal villi in ileal tissue from dam-fed or FS + 17938 mice. B: number of animals with normal histology (NEC scores <2) and with NEC (NEC scores ≥2). n, Number of live animals from which tissue samples could be collected. Terminal ileum of each mouse was harvested at day 5 (or day 3 or 4 for some samples in the FS group). %, Incidence of NEC. *P < 0.05 vs. FS. C: FS and FS + 17938 groups with NEC scores of 2 and 3. *P < 0.05 vs. FS. LR17938 reduced NEC histological injury.