Table 1.
Patient Characteristics
Patient Characteristics | |
---|---|
Median (Range) Age (y) | 54 (20–65) |
FLT3 Mutation Type | |
ITD | 15 (83%) |
TKD | 2 (11%) |
ITD/TKD | 1 (6%) |
FLT3 Mutation Burden | |
Higha | 13 (72%) |
Low | 5 (28%) |
Eastern Cooperative Oncology Group Performance Status | |
0 | 5 (28%) |
1 | 10 (55%) |
2 | 2 (11%) |
3 | 1 (6%) |
Median (Range) White Blood Cell Count (×109/L) | 18 (1.4–196) |
Median (Range) Hemoglobin (g/dL) | 8.5 (6.9–10.8) |
Median (Range) Platelet (×109/L) | 51.5 (18–189) |
Cytogenetics | |
Diploid | 10 (55%) |
Other | 8 (45%) |
≥25% blast-normalized mutation ratio (see Methods section).