Table 2.
Independent prognostic factors for disease-free and overall survival by multivariate analysis
| Variable | Coefficient | Standard error | P -value | Relative risk (95% CI) |
|---|---|---|---|---|
| Disease-free survival |
|
|
|
|
| AST (>50 IU/L) |
0.381 |
0.136 |
0.016 |
1.379 (1.062 to 1.789) |
| Liver cirrhosis |
0.296 |
0.119 |
0.043 |
1.292 (1.009 to 1.654) |
| Perioperative transfusion |
0.301 |
0.118 |
0.008 |
1.386 (1.090 to 1.763) |
| Multiple tumors |
0.553 |
0.134 |
0.013 |
1.564 (1.097 to 2.230) |
| Microvascular invasion |
0.382 |
0.128 |
< 0.001 |
1.604 (1.255 to 2.050) |
| Edmondson-Steiner grade III to IV |
0.321 |
0.131 |
0.014 |
1.379 (1.066 to 1.784) |
| Overall survival |
|
|
|
|
| Serum albumin (≤3.5 g/dL) |
0.587 |
0.166 |
< 0.001 |
1.798 (1.298 to 2.490) |
| Platelet count (≤100,000/mm3) |
0.442 |
0.167 |
0.008 |
1.557 (1.122 to 2.161) |
| Perioperative transfusion |
0.477 |
0.140 |
0.001 |
1.610 (1.224 to 2.118) |
| Perioperative morbidity |
0.353 |
0.143 |
0.013 |
1.423 (1.076 to 1.883) |
| Tumor size (>3 cm) |
0.313 |
0.154 |
0.043 |
1.367 (1.010 to 1.850) |
| Multiple tumors |
0.679 |
0.147 |
< 0.001 |
1.973 (1.478 to 2.633) |
| Macrovascular invasion |
0.581 |
0.227 |
0.011 |
1.789 (1.145 to 2.793) |
| Edmondson-Steiner grade III to IV | 0.419 | 0.147 | 0.004 | 1.521 (1.141 to 2.028) |
AST, aspartate aminotransferase; CI, confidence interval.