Table 3.
Model performance with methods based on five significant SNPs
AUC | Sensitivity | Specificity | Accuracy | Range of 95% CI of AUC | |
---|---|---|---|---|---|
K-nearest neighbors | 0.5589 | 0.3861 | 0.6591 | 0.533 | [0.4293, 0.7101] |
Logistic regression | 0.6044 | 0.4982 | 0.5648 | 0.5346 | [0.4433, 0.7368] |
Naïve Bayes | 0.5996 | 0.3921 | 0.7206 | 0.5686 | [0.4571, 0.7469] |
Random forest | 0.5743 | 0.3169 | 0.7558 | 0.5535 | [0.4405, 0.7233] |
Support vector machine | 0.5494 | 0.2762 | 0.7775 | 0.547 | [0.4187, 0.7086] |
Bayesian additive regression trees | 0.5906 | 0.4779 | 0.5571 | 0.5211 | [0.4385, 0.7211] |
Boosting | 0.6024 | 0.4723 | 0.5544 | 0.5157 | [0.4584, 0.7287] |
Recursive partitioning | 0.5871 | 0.4085 | 0.7218 | 0.5778 | [0.3926, 0.7048] |
Fuzzy rule-based system | 0.5396 | 0.4931 | 0.5006 | 0.4968 | [0.4115, 0.6710] |
AUC, sensitivity, specificity, and accuracy were its mean value in 10-fold validations. Range of 95% CI of AUC represents the range of the 95% CI of AUC in 10-fold Cross-validation. SVM represents support vector machines and Kernel Methods.