Fig. 3.

Lung histopathology. A: quantitation showed and significantly increased allergic inflammation index and goblet cell metaplasia (GCM) scores in the offspring of stressed mothers (RS) and the positive controls compared with negative controls (n = 6/group, *P < 0.05, A and B). Offspring of dexamethasone-injected mothers (Dex) also had a significantly increased GCM score on histopathology compared with negative controls (n ≥ 6/group, *P < 0.05, B). Index scores for the Dex group also trended to be greater than negative controls but did not reach statistical significance. C: representative micrographs of histopathology show increased airway-centered inflammation in positive controls (Pos Ctrl), offspring of stressed mothers (RS), and in offspring of dexamethasone-injected mothers (Dex).