Table 1.
Patient characteristics
| Patient Characteristics | Transfused | Not transfused |
|---|---|---|
| No. patients/ no. hospitalizations |
32,493 / 61,988 |
243,381 / 382,981 |
| % male |
43.7 |
45.8 |
| Age1 |
69.1 (15.3) |
63.7 (17.8) |
| % ≥ 65 years |
65.4 |
51.3 |
| LAPS21,2 |
69.3 (44.1) |
54.2 (38.2) |
| COPS21,3 |
49.7 (45.1) |
34.7 (37.5) |
| Charlson score (median, IQR) |
2, 1 - 3 |
1, 0 – 2 |
| Admission Hemoglobin1,4 |
9.9 (2.4) |
12.9 (1.9) |
| % with these Primary Conditions5 |
|
|
| Gastrointestinal bleeding |
11.5 |
1.4 |
| Orthopedic surgery |
10.9 |
4.6 |
| Malignancy |
9.5 |
5.7 |
| Infection |
11.8 |
13.1 |
| Cardiovascular |
6.2 |
11.5 |
| Other Medical |
33.6 |
43.7 |
| Other Surgical |
16.5 |
20.0 |
| % not “full code” at time of admission |
15.8 |
13.5 |
| Hospital Length of Stay1 |
8.0 (12.2) |
4.6 (4.3) |
| Mortality rate (%) |
|
|
| In-hospital |
6.1 |
2.5 |
| 30-day | 8.7 | 4.6 |
Footnotes
1Mean (Standard Deviation).
2Laboratory Acute Physiology Score, version 2 (LAPS2); physiology-based score which includes vital signs, neurological status, and laboratory results.19 Increasing degrees of physiologic derangement and mortality are reflected in a higher LAPS2, which is a continuous variable that with a range between zero and 282 in this cohort.
3Comorbidity Point Score, version 2 (COPS2); a longitudinal, diagnosis-based score assigned monthly that employs all diagnoses incurred by a patient in the preceding 12 months.19 Increasing values of COPS2 are associated with increasing mortality with a range between zero and 306 in this cohort.
4Admission hemoglobin was available in 410,126 of 444,982 hospitalizations (92.0%).
5Primary Conditions are groupings of related International Classification of Disease codes assigned at the time of admission to the hospital. These codes are further grouped based on the schema used by the Agency for Healthcare Research and Quality’s Healthcare Cost & Utilization Project. See Additional file 1 for additional details.